Endocrine Abstracts

Pituitary adenomas (PA) are benign tumors that develop in pituitary gland. Hormone secreting PA can cause overproduction of pituitary hormones leading to different systemic endocrine disorders (acromegaly, Cushing’s disease and others). Non-secreting PA can promote headaches (stretching of the dural sheath) and visual field defects (chiasma compression). We managed to obtain resected tumor samples from the patient having non-secreting PA, first tumor was resected in 2010,...

Introduction: Pituitary adenomas (PA) are tumours of the anterior pituitary. Despite the benign nature these neoplasms cause increased mortality and morbidity. Clinically relevant PAs affect around 0.1% of population during their lifetime. Currently, there is no human PA cell culture models. Tissue cultures derived from PA surgery materials depending on harvesting conditions can form free floating aggregates called pituispheres (PS) or adherent mesenchymal stromal cells (MSC)....